Searchable abstracts of presentations at key conferences on calcified tissues

ba0001pp102 | Calciotropic and phosphotropic hormones and mineral metabolism | ECTS2013

A genetic polymorphism of osteocalcin is associated with BMI but not with parameters of glucose and lipid metabolism in women with polycystic ovary syndrome

Schwetz Verena , Trummer Olivia , Giuliani Albrecht , Pieber Thomas R , Obermayer-Pietsch Barbara , Lerchbaum Elisabeth

Introduction: Osteocalcin (OC) is a marker of bone formation but also seems to play a hormonal role in the regulation of glucose and energy metabolism. Recently, an association of BMI with a haplotype composed of three single nucleotide polymorphisms (SNPs) in the gene for OC, located on chromosome 1q22, was observed in ethnically homogeneous European pedigrees.Aim: The aim of the study was to test the association of these three polymorphisms in the gene...